Squamous Cell Carcinoma
Metabolic Heterogeneity in Non-small Cell Lung Cancer
Glucose transporter 1 (GLUT1, green) expression is exceptionally elevated in lung squamous cell carcinoma in comparison to lung adenocarcinoma, suggesting significant metabolic heterogeneity among non-small cell lung cancer subtypes. Squamous cell carcinoma marker p63 is shown in pink.
Welcome to the Jay Kim Lab
Jay Kim lab is focused on understanding the heterogeneous metabolic signatures and targetable vulnerabilities in squamous cell carcinoma utilizing genetically engineered mouse models (GEMMs) and patient-derived xenograft (PDX) systems. Another major focus of our research is to understand the significance of hypoxic signaling and metabolic reprogramming of fibroblasts in cancer progression and fibrotic diseases.
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